Cell Sorting Market Overview:
“The global Cell Sorting Market was valued at 337.25 billion in 2023 and is projected to reach 435.67 billion by 2030, growing at a CAGR of 7.6% from 2023-2030.”
The process of cell sorting involves removing cells from an organism and dividing them into different cell types. The cells are marked and identified with markers to pinpoint areas of interest and their effect. Cell differentiation is based on variations in cell size, surface protein expression, and morphology (shape). In numerous biotechnology and biopharmaceutical applications, a heterogeneous mixture of living cells can be sorted. Techniques for sorting cells have evolved over time.
Although still in use and occasionally beneficial, the more primitive systems are far too faulty and ineffective to meet modern demands. Cell sorting is expected to advance research initiatives in the development of new therapies.
Additionally, the ageing population and rising disease prevalence are two other important factors fostering the expansion of pharmaceutical and biotechnology firms. For cell isolation, flow cytometry-based sorting has been widely employed by scientists in biology labs. In this field, significant technological improvements have been seen. HIV patients' infected cells are counted and identified using a test that uses flow cytometry.
Demand Outlook
The growth of the pharmaceutical and biotechnology industries, as well as rising research into cell sorting technologies, are the primary drivers of the worldwide cell sorting market. Microfluidic technology's use for cell sorting is expanding considerably since it is easy to use, quick, and costs less than other methods like FACS and MACS. The massive increase in the prevalence of chronic diseases like cancer and diabetes, the pressing need for the creation of targeted medicines, and the rising cost of healthcare in emerging nations will all be factors driving the market.
Over the course of the anticipated era, technical developments, expanding research and development in cell sorting technologies, and expanding pharmaceutical and biotechnological companies are likely to propel the market's expansion. The pharmaceutical and biotechnology industries' increased use of technologies in research and development is predicted to cause the market to grow faster than average over the course of the forecast period.
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Market Dynamics
Technological Innovations are driving the Global Cell Sorting Market's Steady
High-throughput, high resolution, and more efficient cell sorting techniques have been made possible by continuous improvements in the technology of cell sorting. Methods like flow cytometry, magnetic-activated cells sorting (MACS) and microfluidics-based systems for sorting improve the accuracy of cell sorting as well as speed and efficiency.
In basic and biomedical research, fluorescence-activated cell sorting (FACS) and microscopy are two of the most crucial methods for single-cell phenotyping. Contrary to FACS which can separate hundreds of cells at a time by utilizing basic characteristics such as how intense the fluorescent markers Microscopy provides high-resolution images of cell shapes and inner workings of cells.
To identify cells quickly with fascinating microscopic features, the latest technologies are now combining two approaches and closing a long-standing gap in the field of life sciences.
New Product launches by Major Participants are Driving the growth of the cell sorting market
Market players are implementing their strategies to market, including launch of new products and collaboration with partners to increase their market share. For example in February 2023 the biotechnology company ThinkCyte is a market leader in cutting-edge cell analysis as well as characterization and isolating technology that are based on artificial Intelligence (AI) has announced that it will begin commercially launching its brand-new cell sorting platform, VisionSort.
In addition, VisionSort and its associated ghost cytometry technology have been selected as finalist for The Best New Product and Innovation Awards.
The high costs associated with Cell Sorting Equipment are affecting the Growth of the Market for Cell Sorting
The high costs associated with instruments for sorting cells pose an enormous challenge for the market for cell sorting which could be a risk to its growth and profit. It is a complex expensive device that has to perform multiple tasks at once. Even used, outdated equipment could cost more than $35,000. A used cytometer that has the usual features could cost anything between $80,000 and $150,000.
The price could rise to $500,000 if customers are looking to purchase brand new modern, top of the line equipment with advanced capabilities. Major manufacturers are working to reduce the price of appropriate equipment however, currently research is severely limited due to the lack of funding.
Cell Sorting Market Segment Analysis:
Based on product, technology, application end-user, and region, the global market for cell sorting is divided into these categories.
On the basis of product, cell sorting is subdivided into Cell Sorting Services, Cell Sorters, Reagents, and Consumables. Cell sorting is the process by which one type of cell is distinguished from others present in a sample based on its physical or biological characteristics, such as size, morphological parameters, viability, and the expression of extracellular and intracellular proteins.
Applications for the homogeneous cell population that can be acquired after sorting include research, diagnosis, and therapy. Cell sorting enables the division of cells according to their intra- or extracellular characteristics, such as size, DNA, RNA, and protein connections, as well as the expression of surface proteins. A reagent, also known as an analytical reagent, is a substance or compound that is given to a system in chemistry to either produce a chemical reaction or test whether one has already occurred. Although the terms "reagent" and "reactant" are frequently used synonymously, "reactant" refers to a material that is consumed during a chemical reaction.
Despite being a part of the reaction mechanism, solvents are not typically referred to as reactants. Fluorescence-activated cell sorting (FACS) and immunomagnetic cell sorting are the two main categories of cell sorting techniques. Researchers are attempting to create microfluidic sorting devices, which offer several advantages over the two primary types of cell separation techniques—fluorescence-activated cell sorting and immunomagnetic cell sorting—due to years of improvement and a rise in the need for cell separation.
On the basis of technology, Cell Sorting is further divided into Fluorescence-Based Droplet Cell Sorting and Magnetic-Activated Cell Sorting (MACS). One of the most crucial functions offered by droplet-based microfluidics is fluorescence-activated droplet sorting (FADS). It is currently unable to match with the high-throughput multiplexed sorting capabilities provided by flow cytometry, though. Miltenyi Biotec developed the magnetic-activated cell sorting (MACS) technique to separate different cell populations according to the antigens on their surfaces (CD molecules).
The business has registered the name MACS as a trademark. The technique was created using the MACS system from Miltenyi Biotec, which makes use of superparamagnetic nanoparticles and columns. The superparamagnetic nanoparticles are about 100 nm in size. To capture the targeted cells inside the column, they are employed to tag the specific cells. The column is sandwiched between two permanent magnets, allowing the tagged cells to be caught as the magnetic particle-cell combination travels through it.
While Immunomagnetic cell sorting is sometimes referred to as immunomagnetic cell enrichment, magnetic-activated cell sorting, immunomagnetic cell separation, and MACS, which is a registered brand of Miltenyi GmbH. The principle behind immunomagnetic cell sorting is the magnetic separation of beads. Different firms provide various approaches for cell population enrichment or depletion.
An approach for enriching a heterogeneous mixture of cells based on the expression of cell-surface proteins (antigens) is immunomagnetic cell sorting. The foundation of this method is the coupling of mAbs specific for antigens on the target cell population to small, inert, supra-magnetic particles.
Research and Clinical are the main application areas of the cell sorting market. During the projection period, the sector for academic and research institutions is expected to increase at the greatest CAGR. This is due to the fact that these institutes are conducting an increasing number of research activities.
Research Institutes, Biopharma Companies, and Medical Schools are end-users of the cell sorting market. While biopharma companies refer to the medications created as a result of those biological processes, biotech encompasses goods that are created through biological processes.
Simply said, biotechnology research and production are the sources of all biopharmaceutical goods. While A medical school is a tertiary educational facility or a division thereof, that teaches medicine and confers doctoral degrees on its graduates. The Bachelor of Medicine, Bachelor of Surgery, Master of Medicine, Doctor of Medicine, and Doctor of Osteopathic Medicine are examples of such medical degrees. Many medical schools also offer master's degrees, doctorates in philosophy, and other post-secondary credentials.
Competitive Landscape of the Cell Sorting Market
The major players operating in the global Cell Sorting industry include the major market players are Becton, Union Biometrica, Inc., Beckman Coulter, Inc., Bio-Rad Laboratories, Inc., Miltenyi Biotec GmbH, Sony Biotechnology, Inc., Affymetrix Inc., Sysmex Partec GmbH, On-Chip Biotechnologies Co., Ltd., and Cytonome/ST, LLC
Recent Developments in the Cell Sorting Market
18 January 2022: Sysmex R&D Center Europe and “academist” collaborated in providing academic research funds in Europe.
19 November 2019: Sysmex Launched Caresphere™ QM, an Operational Support System for Testing Quality Management.
Regional Insights:
The largest market share was held by North America. Due to the rising incidence of infectious and chronic diseases, the expansion of the pharmaceutical and biotechnology industries, and the large investments and funding made in cell-based research. According to the National Health Council, 133 million Americans, or more than 39% of the population, suffer from chronic illnesses.
Also, the expanding use of this method in cancer research and the creation of novel treatments in nations like the United States. This is due to the area having sophisticated research infrastructure and growing government support for research in the North America region.
Segments Covered in the Cell Sorting Market
Cell Sorting Market by Product
- Cell Sorting Services
- Cell Sorters
- Reagents
- Consumables
Cell Sorting Market by Technology
- Fluorescence-Based Droplet Cell Sorting
- Magnetic-Activated Cell Sorting (MACS)
Cell Sorting Market by Application
Cell Sorting Market by End-User
- Research Institutes
- Biopharma Companies
- Medical Schools
Cell Sorting Market by Region
- North America
- Europe
- Asia Pacific
- South America
- Middle East and Africa
Frequently asked questions with answers
What is the worth of the global cell sorting market?
The global cell sorting market was valued at 337.25 billion in 2023 and is projected to reach 435.67 billion by 2030, growing at a CAGR of 7.6% from 2023-2030.
Which market segments are covered in the report on the cell sorting market?
Based on product, technology, application end-user, and region the cell sorting market reports divisions are broken down.
Which are the top companies to hold the market share in the cell sorting market?
Key players profiled in the report include Becton, Union Biometrica, Inc., Beckman Coulter, Inc., Bio-Rad Laboratories, Inc., Miltenyi Biotec GmbH, Sony Biotechnology, Inc., Affymetrix Inc., Sysmex Partec GmbH, On-Chip Biotechnologies Co., Ltd., and Cytonome/ST, LLC., and others
Which is the largest regional market for the cell sorting market?
North America held the greatest market share. Due to the expanding prevalence of chronic and infectious diseases, the rise in the number of pharmaceutical and biotechnology businesses, and the significant expenditures and funding made in cell-based research.